Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.2
USERS' SCORE
Good
Based on 4 Reviews
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Zinc (from 150 mg Zinc Bisglycinate) (TRAACS™)
30 mg
273%
Pumpkin Seed Oil (Cold Pressed)
250 mg
†
Top Medical Research Studies
9.5
We observed the effects of zinc on erectile dysfunction in a carefully designed study that involved a double-blind trial. Twenty stable hemodialysis patients participated, receiving either 50 mg of zinc as zinc acetate or a placebo for six months. The goal was to determine if zinc could enhance gonadal function, especially in men who often experience hormonal issues due to kidney problems.
At the end of the study, we noted significant improvements in the zinc-treated group compared to the placebo group. Those receiving zinc had a remarkable increase in plasma zinc levels, testosterone levels, and sperm counts. Specifically, testosterone levels rose from 2.8 to 5.2 ng/mL, and sperm counts doubled from 30 to 63 million/mL, indicating a marked improvement in reproductive health.
Not only did these participants show increased hormone levels, but they also experienced a noticeable drop in luteinizing hormone and follicle-stimulating hormone, suggesting improved gonadal function. Alongside these biochemical changes, many reported better potency, enhanced libido, and increased frequency of intercourse, highlighting zinc’s role in reversing some aspects of erectile dysfunction related to zinc deficiency.
In conclusion, our findings suggest that zinc deficiency can be a reversible factor contributing to erectile dysfunction in hemodialysis patients, offering hope for those struggling with this issue.
At the end of the study, we noted significant improvements in the zinc-treated group compared to the placebo group. Those receiving zinc had a remarkable increase in plasma zinc levels, testosterone levels, and sperm counts. Specifically, testosterone levels rose from 2.8 to 5.2 ng/mL, and sperm counts doubled from 30 to 63 million/mL, indicating a marked improvement in reproductive health.
Not only did these participants show increased hormone levels, but they also experienced a noticeable drop in luteinizing hormone and follicle-stimulating hormone, suggesting improved gonadal function. Alongside these biochemical changes, many reported better potency, enhanced libido, and increased frequency of intercourse, highlighting zinc’s role in reversing some aspects of erectile dysfunction related to zinc deficiency.
In conclusion, our findings suggest that zinc deficiency can be a reversible factor contributing to erectile dysfunction in hemodialysis patients, offering hope for those struggling with this issue.
Read More
9
Zinc improves erectile dysfunction
We explored the impact of zinc treatment on erectile dysfunction, particularly in rats exposed to lead. The study involved twenty male Wistar rats, randomly assigned to four different groups: a control group, a group receiving zinc treatment, a group exposed to lead, and a group that received both lead and zinc therapy. This design allowed us to see how zinc could counteract the adverse effects of lead exposure on sexual function.
Our findings revealed that zinc co-administration significantly benefitted rats affected by lead, showing improvements in key sexual performance metrics. We observed enhancements in penile weight and increased latencies and frequencies of mating behaviors such as mounting, intromission, and ejaculation. In addition to these behavioral improvements, zinc treatment also helped restore important biological signals that drive sexual function, including nitric oxide and testosterone levels.
Overall, our study indicates that zinc can play a vital role in mitigating lead-induced sexual and erectile dysfunction by reducing oxidative stress and enhancing hormonal balance. This suggests potential therapeutic benefits of zinc in similar conditions affecting sexual health.
Our findings revealed that zinc co-administration significantly benefitted rats affected by lead, showing improvements in key sexual performance metrics. We observed enhancements in penile weight and increased latencies and frequencies of mating behaviors such as mounting, intromission, and ejaculation. In addition to these behavioral improvements, zinc treatment also helped restore important biological signals that drive sexual function, including nitric oxide and testosterone levels.
Overall, our study indicates that zinc can play a vital role in mitigating lead-induced sexual and erectile dysfunction by reducing oxidative stress and enhancing hormonal balance. This suggests potential therapeutic benefits of zinc in similar conditions affecting sexual health.
Read More
9
Zinc aids erectile function in rats
We investigated the impact of zinc on erectile dysfunction associated with HAART (Highly Active Antiretroviral Therapy) in a controlled study involving male Wistar rats. The research included four groups: a control group, a zinc-only group, a HAART-only group, and a group treated with both HAART and zinc. Our treatment lasted for eight weeks, allowing us to observe the effects of zinc supplementation in the context of HAART-induced sexual dysfunction.
The results were quite promising. We found that zinc significantly reduced the negative impacts HAART had on key factors related to sexual performance. Specifically, zinc treatment improved latency times for mating behaviors and enhanced overall motivation to engage in sexual activity. It also increased important biochemical markers such as nitric oxide and testosterone levels while decreasing harmful enzyme activities that could contribute to erectile dysfunction.
Beyond just improving physical responses, zinc helped restore a normal balance of oxidative stress in the penis. This means that the antioxidant properties of zinc were crucial in addressing inflammation and oxidative damage caused by HAART. In essence, we learned that zinc might be a valuable addition to treatment plans for maintaining sexual health in individuals undergoing HAART.
The results were quite promising. We found that zinc significantly reduced the negative impacts HAART had on key factors related to sexual performance. Specifically, zinc treatment improved latency times for mating behaviors and enhanced overall motivation to engage in sexual activity. It also increased important biochemical markers such as nitric oxide and testosterone levels while decreasing harmful enzyme activities that could contribute to erectile dysfunction.
Beyond just improving physical responses, zinc helped restore a normal balance of oxidative stress in the penis. This means that the antioxidant properties of zinc were crucial in addressing inflammation and oxidative damage caused by HAART. In essence, we learned that zinc might be a valuable addition to treatment plans for maintaining sexual health in individuals undergoing HAART.
Read More
Most Useful Reviews
7.5
Improved testosterone level
4 people found this helpful
Zinc is essential for maintaining a normal testosterone level. Insufficient testosterone can lead to fatigue, poor libido, erectile dysfunction, and even loss of muscle mass. Adequate zinc may help prevent prostate disease and improve sperm quality for those with fertility needs. It also supports skin and hair health, mitigating issues like hair loss and dry skin. For women, zinc may alleviate premenstrual syndrome and postmenopausal vaginal dryness, enhancing sexual quality of life.
Read More
9
Enhanced immunity
It’s nearly impossible to fully replace zinc deficiency through diet alone, but zinc is crucial for immunity, visual acuity, hair health, and preventing sexual dysfunctions. I've noticed significant improvement in my hair health. After injuring my finger, the wound healed remarkably well in just a few days. I take zinc combined with other vitamins and, while I can't pinpoint which one had the most effect, the results speak for themselves. I take a zinc complex for preventive health every six months.
Read More
9
Enhanced erectile function
The dose and form of zinc attracted me to this product; I prefer glycinate over other forms. My husband has noticed increased erectile function, which highlights zinc’s role in inhibiting the enzyme that converts testosterone to dihydrotestosterone. It seems beneficial for improving erectile dysfunction.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.2
- All Researches
9.5
We observed the effects of zinc on erectile dysfunction in a carefully designed study that involved a double-blind trial. Twenty stable hemodialysis patients participated, receiving either 50 mg of zinc as zinc acetate or a placebo for six months. The goal was to determine if zinc could enhance gonadal function, especially in men who often experience hormonal issues due to kidney problems.
At the end of the study, we noted significant improvements in the zinc-treated group compared to the placebo group. Those receiving zinc had a remarkable increase in plasma zinc levels, testosterone levels, and sperm counts. Specifically, testosterone levels rose from 2.8 to 5.2 ng/mL, and sperm counts doubled from 30 to 63 million/mL, indicating a marked improvement in reproductive health.
Not only did these participants show increased hormone levels, but they also experienced a noticeable drop in luteinizing hormone and follicle-stimulating hormone, suggesting improved gonadal function. Alongside these biochemical changes, many reported better potency, enhanced libido, and increased frequency of intercourse, highlighting zinc’s role in reversing some aspects of erectile dysfunction related to zinc deficiency.
In conclusion, our findings suggest that zinc deficiency can be a reversible factor contributing to erectile dysfunction in hemodialysis patients, offering hope for those struggling with this issue.
At the end of the study, we noted significant improvements in the zinc-treated group compared to the placebo group. Those receiving zinc had a remarkable increase in plasma zinc levels, testosterone levels, and sperm counts. Specifically, testosterone levels rose from 2.8 to 5.2 ng/mL, and sperm counts doubled from 30 to 63 million/mL, indicating a marked improvement in reproductive health.
Not only did these participants show increased hormone levels, but they also experienced a noticeable drop in luteinizing hormone and follicle-stimulating hormone, suggesting improved gonadal function. Alongside these biochemical changes, many reported better potency, enhanced libido, and increased frequency of intercourse, highlighting zinc’s role in reversing some aspects of erectile dysfunction related to zinc deficiency.
In conclusion, our findings suggest that zinc deficiency can be a reversible factor contributing to erectile dysfunction in hemodialysis patients, offering hope for those struggling with this issue.
Read More
9
Zinc improves erectile dysfunction
We explored the impact of zinc treatment on erectile dysfunction, particularly in rats exposed to lead. The study involved twenty male Wistar rats, randomly assigned to four different groups: a control group, a group receiving zinc treatment, a group exposed to lead, and a group that received both lead and zinc therapy. This design allowed us to see how zinc could counteract the adverse effects of lead exposure on sexual function.
Our findings revealed that zinc co-administration significantly benefitted rats affected by lead, showing improvements in key sexual performance metrics. We observed enhancements in penile weight and increased latencies and frequencies of mating behaviors such as mounting, intromission, and ejaculation. In addition to these behavioral improvements, zinc treatment also helped restore important biological signals that drive sexual function, including nitric oxide and testosterone levels.
Overall, our study indicates that zinc can play a vital role in mitigating lead-induced sexual and erectile dysfunction by reducing oxidative stress and enhancing hormonal balance. This suggests potential therapeutic benefits of zinc in similar conditions affecting sexual health.
Our findings revealed that zinc co-administration significantly benefitted rats affected by lead, showing improvements in key sexual performance metrics. We observed enhancements in penile weight and increased latencies and frequencies of mating behaviors such as mounting, intromission, and ejaculation. In addition to these behavioral improvements, zinc treatment also helped restore important biological signals that drive sexual function, including nitric oxide and testosterone levels.
Overall, our study indicates that zinc can play a vital role in mitigating lead-induced sexual and erectile dysfunction by reducing oxidative stress and enhancing hormonal balance. This suggests potential therapeutic benefits of zinc in similar conditions affecting sexual health.
Read More
9
Zinc aids erectile function in rats
We investigated the impact of zinc on erectile dysfunction associated with HAART (Highly Active Antiretroviral Therapy) in a controlled study involving male Wistar rats. The research included four groups: a control group, a zinc-only group, a HAART-only group, and a group treated with both HAART and zinc. Our treatment lasted for eight weeks, allowing us to observe the effects of zinc supplementation in the context of HAART-induced sexual dysfunction.
The results were quite promising. We found that zinc significantly reduced the negative impacts HAART had on key factors related to sexual performance. Specifically, zinc treatment improved latency times for mating behaviors and enhanced overall motivation to engage in sexual activity. It also increased important biochemical markers such as nitric oxide and testosterone levels while decreasing harmful enzyme activities that could contribute to erectile dysfunction.
Beyond just improving physical responses, zinc helped restore a normal balance of oxidative stress in the penis. This means that the antioxidant properties of zinc were crucial in addressing inflammation and oxidative damage caused by HAART. In essence, we learned that zinc might be a valuable addition to treatment plans for maintaining sexual health in individuals undergoing HAART.
The results were quite promising. We found that zinc significantly reduced the negative impacts HAART had on key factors related to sexual performance. Specifically, zinc treatment improved latency times for mating behaviors and enhanced overall motivation to engage in sexual activity. It also increased important biochemical markers such as nitric oxide and testosterone levels while decreasing harmful enzyme activities that could contribute to erectile dysfunction.
Beyond just improving physical responses, zinc helped restore a normal balance of oxidative stress in the penis. This means that the antioxidant properties of zinc were crucial in addressing inflammation and oxidative damage caused by HAART. In essence, we learned that zinc might be a valuable addition to treatment plans for maintaining sexual health in individuals undergoing HAART.
Read More
7
We explored the role of zinc in treating erectile dysfunction, particularly in patients with chronic kidney disease (CKD). Several studies were analyzed, focusing primarily on the effectiveness of zinc compared to a placebo.
Through this review, we observed that while oral zinc treatment showed some promise in enhancing testosterone levels, particularly in one study, the overall findings were mixed. For instance, when zinc was added to dialysate, there was no significant increase in testosterone levels, which is crucial for sexual function.
The research on zinc and its effects on erectile dysfunction remains limited, and there's a clear need for more extensive studies. It's important to note that while PDE5 inhibitors, another treatment option, showed noteworthy improvements, zinc alone did not consistently deliver compelling results. This indicates that while zinc might have potential, it shouldn’t be viewed as a standalone solution for erectile dysfunction in CKD patients at this stage.
Through this review, we observed that while oral zinc treatment showed some promise in enhancing testosterone levels, particularly in one study, the overall findings were mixed. For instance, when zinc was added to dialysate, there was no significant increase in testosterone levels, which is crucial for sexual function.
The research on zinc and its effects on erectile dysfunction remains limited, and there's a clear need for more extensive studies. It's important to note that while PDE5 inhibitors, another treatment option, showed noteworthy improvements, zinc alone did not consistently deliver compelling results. This indicates that while zinc might have potential, it shouldn’t be viewed as a standalone solution for erectile dysfunction in CKD patients at this stage.
Read More
7
Zinc's mixed impact on dysfunction
We conducted a study to understand how zinc might influence erectile dysfunction, particularly in men taking hydrochlorothiazide, a medication for high blood pressure. The research involved 39 middle-aged men on hydrochlorothiazide and 27 healthy men not on medication. We found a notably higher rate of sexual dysfunction among those taking hydrochlorothiazide—56% compared to just 11% in the control group.
Importantly, we noticed that hydrochlorothiazide affected serum zinc levels in some patients. In further investigation, we divided 22 men with sexual dysfunction into two groups. One received zinc supplements for a month, while the other received magnesium. After this period, we observed that zinc levels in the blood returned to normal for only eight out of the twenty-two patients, with improvements in sexual dysfunction symptoms reported by five of them.
While our findings suggest that low zinc levels might be linked to sexual dysfunction, the overall impact of zinc supplementation remains inconclusive. In fact, the improvements we saw weren't consistent across the board, and the definitive role of zinc in addressing sexual dysfunction is still up for debate.
Importantly, we noticed that hydrochlorothiazide affected serum zinc levels in some patients. In further investigation, we divided 22 men with sexual dysfunction into two groups. One received zinc supplements for a month, while the other received magnesium. After this period, we observed that zinc levels in the blood returned to normal for only eight out of the twenty-two patients, with improvements in sexual dysfunction symptoms reported by five of them.
While our findings suggest that low zinc levels might be linked to sexual dysfunction, the overall impact of zinc supplementation remains inconclusive. In fact, the improvements we saw weren't consistent across the board, and the definitive role of zinc in addressing sexual dysfunction is still up for debate.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Improved testosterone level
4 people found this helpful
Zinc is essential for maintaining a normal testosterone level. Insufficient testosterone can lead to fatigue, poor libido, erectile dysfunction, and even loss of muscle mass. Adequate zinc may help prevent prostate disease and improve sperm quality for those with fertility needs. It also supports skin and hair health, mitigating issues like hair loss and dry skin. For women, zinc may alleviate premenstrual syndrome and postmenopausal vaginal dryness, enhancing sexual quality of life.
Read More
9
Enhanced immunity
It’s nearly impossible to fully replace zinc deficiency through diet alone, but zinc is crucial for immunity, visual acuity, hair health, and preventing sexual dysfunctions. I've noticed significant improvement in my hair health. After injuring my finger, the wound healed remarkably well in just a few days. I take zinc combined with other vitamins and, while I can't pinpoint which one had the most effect, the results speak for themselves. I take a zinc complex for preventive health every six months.
Read More
9
Enhanced erectile function
The dose and form of zinc attracted me to this product; I prefer glycinate over other forms. My husband has noticed increased erectile function, which highlights zinc’s role in inhibiting the enzyme that converts testosterone to dihydrotestosterone. It seems beneficial for improving erectile dysfunction.
Read More
7.5
Increased sexual energy
I’ve experienced less stomach pain, nausea, and an increase in sexual energy since taking zinc. At 40, I take one tablet daily for my sexual health, totalling 60mg per day. Although it feels like a high dose, I’ve not experienced side effects. I always take it after meals, as taking it on an empty stomach made me feel nauseous. This zinc glycine formulation appears gentler on my stomach and positively impacts my sex life, helping with erectile dysfunction.
Read More
Frequently Asked Questions
9
Enhanced erectile function
The dose and form of zinc attracted me to this product; I prefer glycinate over other forms. My husband has noticed increased erectile function, which highlights zinc’s role in inhibiting the enzyme that converts testosterone to dihydrotestosterone. It seems beneficial for improving erectile dysfunction.
7.5
Increased sexual energy
I’ve experienced less stomach pain, nausea, and an increase in sexual energy since taking zinc. At 40, I take one tablet daily for my sexual health, totalling 60mg per day. Although it feels like a high dose, I’ve not experienced side effects. I always take it after meals, as taking it on an empty stomach made me feel nauseous. This zinc glycine formulation appears gentler on my stomach and positively impacts my sex life, helping with erectile dysfunction.
9
Enhanced immunity
It’s nearly impossible to fully replace zinc deficiency through diet alone, but zinc is crucial for immunity, visual acuity, hair health, and preventing sexual dysfunctions. I've noticed significant improvement in my hair health. After injuring my finger, the wound healed remarkably well in just a few days. I take zinc combined with other vitamins and, while I can't pinpoint which one had the most effect, the results speak for themselves. I take a zinc complex for preventive health every six months.
7.5
Improved testosterone level
4 people found this helpful
Zinc is essential for maintaining a normal testosterone level. Insufficient testosterone can lead to fatigue, poor libido, erectile dysfunction, and even loss of muscle mass. Adequate zinc may help prevent prostate disease and improve sperm quality for those with fertility needs. It also supports skin and hair health, mitigating issues like hair loss and dry skin. For women, zinc may alleviate premenstrual syndrome and postmenopausal vaginal dryness, enhancing sexual quality of life.
9
Zinc improves erectile dysfunction
We explored the impact of zinc treatment on erectile dysfunction, particularly in rats exposed to lead. The study involved twenty male Wistar rats, randomly assigned to four different groups: a control group, a group receiving zinc treatment, a group exposed to lead, and a group that received both lead and zinc therapy. This design allowed us to see how zinc could counteract the adverse effects of lead exposure on sexual function.
Our findings revealed that zinc co-administration significantly benefitted rats affected by lead, showing improvements in key sexual performance metrics. We observed enhancements in penile weight and increased latencies and frequencies of mating behaviors such as mounting, intromission, and ejaculation. In addition to these behavioral improvements, zinc treatment also helped restore important biological signals that drive sexual function, including nitric oxide and testosterone levels.
Overall, our study indicates that zinc can play a vital role in mitigating lead-induced sexual and erectile dysfunction by reducing oxidative stress and enhancing hormonal balance. This suggests potential therapeutic benefits of zinc in similar conditions affecting sexual health.
Our findings revealed that zinc co-administration significantly benefitted rats affected by lead, showing improvements in key sexual performance metrics. We observed enhancements in penile weight and increased latencies and frequencies of mating behaviors such as mounting, intromission, and ejaculation. In addition to these behavioral improvements, zinc treatment also helped restore important biological signals that drive sexual function, including nitric oxide and testosterone levels.
Overall, our study indicates that zinc can play a vital role in mitigating lead-induced sexual and erectile dysfunction by reducing oxidative stress and enhancing hormonal balance. This suggests potential therapeutic benefits of zinc in similar conditions affecting sexual health.
9
Zinc aids erectile function in rats
We investigated the impact of zinc on erectile dysfunction associated with HAART (Highly Active Antiretroviral Therapy) in a controlled study involving male Wistar rats. The research included four groups: a control group, a zinc-only group, a HAART-only group, and a group treated with both HAART and zinc. Our treatment lasted for eight weeks, allowing us to observe the effects of zinc supplementation in the context of HAART-induced sexual dysfunction.
The results were quite promising. We found that zinc significantly reduced the negative impacts HAART had on key factors related to sexual performance. Specifically, zinc treatment improved latency times for mating behaviors and enhanced overall motivation to engage in sexual activity. It also increased important biochemical markers such as nitric oxide and testosterone levels while decreasing harmful enzyme activities that could contribute to erectile dysfunction.
Beyond just improving physical responses, zinc helped restore a normal balance of oxidative stress in the penis. This means that the antioxidant properties of zinc were crucial in addressing inflammation and oxidative damage caused by HAART. In essence, we learned that zinc might be a valuable addition to treatment plans for maintaining sexual health in individuals undergoing HAART.
The results were quite promising. We found that zinc significantly reduced the negative impacts HAART had on key factors related to sexual performance. Specifically, zinc treatment improved latency times for mating behaviors and enhanced overall motivation to engage in sexual activity. It also increased important biochemical markers such as nitric oxide and testosterone levels while decreasing harmful enzyme activities that could contribute to erectile dysfunction.
Beyond just improving physical responses, zinc helped restore a normal balance of oxidative stress in the penis. This means that the antioxidant properties of zinc were crucial in addressing inflammation and oxidative damage caused by HAART. In essence, we learned that zinc might be a valuable addition to treatment plans for maintaining sexual health in individuals undergoing HAART.
9.5
We observed the effects of zinc on erectile dysfunction in a carefully designed study that involved a double-blind trial. Twenty stable hemodialysis patients participated, receiving either 50 mg of zinc as zinc acetate or a placebo for six months. The goal was to determine if zinc could enhance gonadal function, especially in men who often experience hormonal issues due to kidney problems.
At the end of the study, we noted significant improvements in the zinc-treated group compared to the placebo group. Those receiving zinc had a remarkable increase in plasma zinc levels, testosterone levels, and sperm counts. Specifically, testosterone levels rose from 2.8 to 5.2 ng/mL, and sperm counts doubled from 30 to 63 million/mL, indicating a marked improvement in reproductive health.
Not only did these participants show increased hormone levels, but they also experienced a noticeable drop in luteinizing hormone and follicle-stimulating hormone, suggesting improved gonadal function. Alongside these biochemical changes, many reported better potency, enhanced libido, and increased frequency of intercourse, highlighting zinc’s role in reversing some aspects of erectile dysfunction related to zinc deficiency.
In conclusion, our findings suggest that zinc deficiency can be a reversible factor contributing to erectile dysfunction in hemodialysis patients, offering hope for those struggling with this issue.
At the end of the study, we noted significant improvements in the zinc-treated group compared to the placebo group. Those receiving zinc had a remarkable increase in plasma zinc levels, testosterone levels, and sperm counts. Specifically, testosterone levels rose from 2.8 to 5.2 ng/mL, and sperm counts doubled from 30 to 63 million/mL, indicating a marked improvement in reproductive health.
Not only did these participants show increased hormone levels, but they also experienced a noticeable drop in luteinizing hormone and follicle-stimulating hormone, suggesting improved gonadal function. Alongside these biochemical changes, many reported better potency, enhanced libido, and increased frequency of intercourse, highlighting zinc’s role in reversing some aspects of erectile dysfunction related to zinc deficiency.
In conclusion, our findings suggest that zinc deficiency can be a reversible factor contributing to erectile dysfunction in hemodialysis patients, offering hope for those struggling with this issue.
7
We explored the role of zinc in treating erectile dysfunction, particularly in patients with chronic kidney disease (CKD). Several studies were analyzed, focusing primarily on the effectiveness of zinc compared to a placebo.
Through this review, we observed that while oral zinc treatment showed some promise in enhancing testosterone levels, particularly in one study, the overall findings were mixed. For instance, when zinc was added to dialysate, there was no significant increase in testosterone levels, which is crucial for sexual function.
The research on zinc and its effects on erectile dysfunction remains limited, and there's a clear need for more extensive studies. It's important to note that while PDE5 inhibitors, another treatment option, showed noteworthy improvements, zinc alone did not consistently deliver compelling results. This indicates that while zinc might have potential, it shouldn’t be viewed as a standalone solution for erectile dysfunction in CKD patients at this stage.
Through this review, we observed that while oral zinc treatment showed some promise in enhancing testosterone levels, particularly in one study, the overall findings were mixed. For instance, when zinc was added to dialysate, there was no significant increase in testosterone levels, which is crucial for sexual function.
The research on zinc and its effects on erectile dysfunction remains limited, and there's a clear need for more extensive studies. It's important to note that while PDE5 inhibitors, another treatment option, showed noteworthy improvements, zinc alone did not consistently deliver compelling results. This indicates that while zinc might have potential, it shouldn’t be viewed as a standalone solution for erectile dysfunction in CKD patients at this stage.
4
Zinc treatment offers limited benefits
We explored the effectiveness of zinc treatment for erectile dysfunction, particularly in patients with chronic kidney disease (CKD). The study included fourteen trials with a total of 328 patients. These trials focused on how zinc influences sexual health and whether it can improve erectile function.
When we looked specifically at zinc, we saw that while there was a notable improvement in testosterone levels with oral zinc treatment, the addition of zinc to dialysis did not significantly boost testosterone levels. This indicates that zinc might have some benefits, but the evidence is not strong enough to conclude its effectiveness as a standalone treatment for erectile dysfunction.
Overall, while some positive effects were observed, the results suggest that more research is needed. We found limited evidence supporting the routine use of zinc for managing sexual dysfunction in CKD patients. The need for further studies highlights the complexity of addressing sexual health in this population.
When we looked specifically at zinc, we saw that while there was a notable improvement in testosterone levels with oral zinc treatment, the addition of zinc to dialysis did not significantly boost testosterone levels. This indicates that zinc might have some benefits, but the evidence is not strong enough to conclude its effectiveness as a standalone treatment for erectile dysfunction.
Overall, while some positive effects were observed, the results suggest that more research is needed. We found limited evidence supporting the routine use of zinc for managing sexual dysfunction in CKD patients. The need for further studies highlights the complexity of addressing sexual health in this population.
5
We explored the role of zinc in treating erectile dysfunction (ED) in rats suffering from hyperhomocysteinemia, a condition marked by high levels of homocysteine that can lead to ED. In this study, we worked with 40 male Wistar rats. Ten were used as normal controls, while the remaining 30 were divided into three groups after developing hyperhomocysteinemia through a high methionine diet.
One group continued with the high methionine diet, while another received betaine hydrochloride, and the third group was given zinc porphyrin IX. We recorded the frequency of penile erections over 4 weeks and measured the levels of homocysteine, carbon monoxide (CO), and heme oxygenase 2 (HO-2) in the corpus cavernosum of the rats.
While the study examined zinc's effect amid other treatments, results indicated that the presence of zinc did not lead to a significant increase in erectile function compared to the control group. We noted decreased levels of CO and HO-2 closely linked to the onset of ED in the hyperhomocysteinemic rats. While betaine hydrochloride showed promise in reducing homocysteine levels and enhancing CO content, zinc's isolated impact wasn't fully determined in this mixture of treatments.
Overall, it's clear that further research is needed to evaluate zinc's effectiveness when it stands alone as a treatment for erectile dysfunction.
One group continued with the high methionine diet, while another received betaine hydrochloride, and the third group was given zinc porphyrin IX. We recorded the frequency of penile erections over 4 weeks and measured the levels of homocysteine, carbon monoxide (CO), and heme oxygenase 2 (HO-2) in the corpus cavernosum of the rats.
While the study examined zinc's effect amid other treatments, results indicated that the presence of zinc did not lead to a significant increase in erectile function compared to the control group. We noted decreased levels of CO and HO-2 closely linked to the onset of ED in the hyperhomocysteinemic rats. While betaine hydrochloride showed promise in reducing homocysteine levels and enhancing CO content, zinc's isolated impact wasn't fully determined in this mixture of treatments.
Overall, it's clear that further research is needed to evaluate zinc's effectiveness when it stands alone as a treatment for erectile dysfunction.
References
- Besong EE, Akhigbe TM, Ashonibare PJ, Oladipo AA, Obimma JN, et al. Zinc improves sexual performance and erectile function by preventing penile oxidative injury and upregulating circulating testosterone in lead-exposed rats. Redox Rep. 2023;28:2225675. 10.1080/13510002.2023.2225675
- Akhigbe RE, Hamed MA, Odetayo AF, Akhigbe TM, Oyedokun PA. Zinc improves sexual and erectile function in HAART-treated rats via the upregulation of erectogenic enzymes and maintenance of redox balance. Aging Male. 2023;26:2205517. 10.1080/13685538.2023.2205517
- Qin WB, Huang WJ, Chi BJ, He HL, Chen DY, et al. [Effects of plasma Hcy on the contents of CO and HO-2 in the corpus cavernosum of ED rats with hyperhomocysteinemia]. Zhonghua Nan Ke Xue. 2013;19:398.
- Vecchio M, Navaneethan SD, Johnson DW, Lucisano G, Graziano G, et al. Interventions for treating sexual dysfunction in patients with chronic kidney disease. Cochrane Database Syst Rev. 2010. 10.1002/14651858.CD007747.pub2
- Vecchio M, Navaneethan SD, Johnson DW, Lucisano G, Graziano G, et al. Treatment options for sexual dysfunction in patients with chronic kidney disease: a systematic review of randomized controlled trials. Clin J Am Soc Nephrol. 2010;5:985. 10.2215/CJN.09081209
- Khedun SM, Naicker T, Maharaj B. Zinc, hydrochlorothiazide and sexual dysfunction. Cent Afr J Med. 1995;41:312.
- Mahajan SK, Abbasi AA, Prasad AS, Rabbani P, Briggs WA, et al. Effect of oral zinc therapy on gonadal function in hemodialysis patients. A double-blind study. Ann Intern Med. 1982;97:357.
